Virtual Bioequivalence Studio · 2.0
Predict. Explain. Improve. Re-simulate.
Build paired Reference/Test product twins, propagate formulation and physiology through virtual humans, inspect AUC/Cmax and BE statistics, then identify the experiment or formulation change most likely to reduce uncertainty.
Product TwinsDissolutionPBBM/PBPK anchorVirtual HumanPK/NCAABE/NTI/HVDUncertaintyVOIDecision Passport
Decision support
Not runVirtual BE evidence
Run the governed simulation. This workspace will show paired PK, BE statistics, physiology, model credibility, uncertainty and the next experiment.
AUC GMR--Test / Reference
Cmax GMR--Test / Reference
Virtual-trial BE rate--Development simulation
Credibility--C0–C4
f2--
Evidence readiness--
Dominant uncertainty--
PBPK anchor--
RLD vs Test dissolution
ReferenceTest
Median virtual concentration–time
ReferenceTest
--
Human review required · Regulatory BE established: No
Mechanistic layer
Product twins + virtual human
Digital twins
Physiology dimensions
Virtual-subject ratios
| ID | Age | Weight | Gastric pH | AUC T/R | Cmax T/R |
|---|
Uncertainty intelligence
What is driving the decision?
Uncertainty decomposition
Sensitivity tornado
Value of information — what should we measure next?
Formulation scenario studio
Compare and optimize candidates
Run scenario comparison or formulation optimization after configuring the base case.
Study-design optimizer
Translate model risk into study planning
No study-design result yet.
Bayesian pilot update
Pilot evidence has not been incorporated.
Governed evidence
Decision Passport
Run vBE to generate a traceable passport.